Clinical Pharmacology And Chemotherapy

1. Explain the principles of pharmacokinetics and pharmacodynamics.
2. Identify different drug dosage forms and routes of administration.
3. Describe the mechanisms of action of drugs acting on the autonomic nervous system.
4. Apply knowledge of cardiovascular drugs to treat common heart conditions.
5. Discuss the use of chemotherapeutic agents in treating infections and cancer.
6. Compare and contrast traditional and orthodox medicine practices.

13 weeks, about 36 hours in total. Yours will differ.

1. Week 1Module 1: Clinical Pharmacology and Pharmacokinetics

   • Unit 1: Introduction to Clinical Pharmacology and Chemotherapy · 2 hours

     Define clinical pharmacology, chemotherapy, toxicology, drug, pharmacokinetics, and pharmacodynamics.. Understand the actions of drugs on various systems of the body.. Identify different dosage forms and routes of drug administration.. Compare traditional medicine and orthodox medicine..

2. Week 2Module 1: Clinical Pharmacology and Pharmacokinetics

   • Unit 2: Different Dosage Forms · 2 hours

     Define drug, dosage forms, and chemical names.. Understand essential drugs and their criteria.. Describe various dosage forms and give examples.. Differentiate between chemical, non-proprietary, and proprietary drug names..

3. Week 3Module 1: Clinical Pharmacology and Pharmacokinetics

   • Unit 3: Pharmacokinetics and Routes of Drug Administration · 2 hours

     Acquaint yourself with the various routes of drug administration.. Understand absorption, distribution, metabolism, and elimination of drugs.. Distinguish between bioavailability, bioequivalence, and therapeutic equivalence.. Understand the concept of pharmacokinetics..

4. Week 4Module 1: Clinical Pharmacology and Pharmacokinetics

   • Unit 4: Basic and Clinical Evaluation of New Drugs · 2 hours

     Understand the process involved in the development of new drugs.. Learn about preclinical safety and toxicity testing.. Understand the preclinical evaluation of drugs in humans.. Describe the role of NAFDAC in drug regulation..

5. Week 5Module 2: Interaction of Drugs with the Body Systems

   • Unit 1: Autonomic Nervous System · 2 hours

     Understand the process of synthesis, storage, release, and removal of acetylcholine.. Learn about pharmacological intervention in neurotransmission.. Understand the mechanism of action of sympathomimetic drugs.. Know the clinical uses of catecholamines and their adverse reactions..

6. Week 6Module 2: Interaction of Drugs with the Body Systems

   • Unit 2: Drugs acting on the Respiratory System Including Anti Asthmatic Drugs · 2 hours

     Understand the etiology of asthma.. Learn about the pathogenesis and clinical manifestation of asthma.. Identify the various drugs used in the treatment of asthma.. Differentiate between intrinsic and extrinsic asthma..

7. Week 7Module 2: Interaction of Drugs with the Body Systems

   • Unit 3: Drugs acting on the Endocrine System including Anti-diabetic Drugs · 2 hours

     Define diabetes and its pathophysiology.. Classify drugs used in the treatment of diabetes.. Understand the etiology and pathophysiology of diabetes mellitus.. Learn about insulin and oral hypoglycemic agents..

8. Week 8Module 2: Interaction of Drugs with the Body Systems

   • Unit 4: Drugs used in Acid Peptic Disease · 2 hours

     Understand what acid peptic diseases are.. Identify the classes of drugs used in treating acid peptic diseases.. Learn about the contraindications in acid peptic diseases.. Describe the mechanisms of action of antacids, H2-receptor antagonists, and proton pump inhibitors..

9. Week 9Module 3: Drugs Acting on the Cardiovascular System

   • Unit 1: Congestive Heart Failure and Drugs Used · 2 hours

     Understand the definition of congestive heart failure and its pathophysiology.. Identify the drugs used in the treatment of congestive heart failure.. Learn about the etiology and pathology of congestive heart failure.. Describe the roles of digitalis, diuretics, and vasodilators in treating CHF..

   • Unit 2: Cardiac Arrhythmia and Drugs Used · 2 hours

     Define cardiac arrhythmia.. Outline the classes of drugs used in the treatment of cardiac arrhythmia.. Learn about the etiology and pathogenesis of cardiac arrhythmias.. Describe the mechanisms of action of Class I, II, III, and IV antiarrhythmic drugs..

10. Week 10Module 3: Drugs Acting on the Cardiovascular System

    • Unit 3: Angina Pectoris and Drugs Used · 2 hours

      Define angina pectoris.. Outline the three main groups of drugs used in the treatment of angina pectoris.. Learn about the etiology and pathology of angina pectoris.. Describe the roles of nitrates, beta-blockers, and calcium channel blockers in treating angina..

    • Unit 4: Hypertension and Anti-hypertensive drugs · 2 hours

      Understand the physiologic control of blood pressure.. Learn about the diagnosis of hypertension.. Understand the basic pharmacology of some antihypertensive agents.. Learn the meaning of hypertensive urgencies and hypertensive emergencies..

11. Week 11Module 4: Chemotherapeutic Drugs

    • Unit 1: Chloramphenicol and Tetracyclines as Antibiotics · 2 hours

      Understand the pharmacokinetics and clinical uses of chloramphenicol.. Understand the pharmacokinetics and clinical uses of tetracyclines.. Learn about the adverse reactions of chloramphenicol and tetracyclines.. Compare and contrast the mechanisms of action of chloramphenicol and tetracyclines..

    • Unit 2: Sulphonamides, Trimethoprim and Quinolones as Antibiotics · 2 hours

      Understand the mechanisms of action of sulfonamides and trimethoprim.. Learn about the pharmacokinetics and clinical uses of sulfonamides and trimethoprim.. Understand the pharmacokinetics and clinical uses of quinolones.. Learn about the adverse reactions of sulfonamides, trimethoprim, and quinolones..

12. Week 12Module 4: Chemotherapeutic Drugs

    • Unit 3: Beta Lactam Antibiotics and Other Inhibitors of Cell wall Synthesis · 2 hours

      Understand the mechanism of action of penicillins and cephalosporins.. Learn about the clinical uses of penicillins and cephalosporins.. Understand the pharmacokinetics of penicillins and cephalosporins.. Classify penicillins and cephalosporins based on their spectrum of activity..

    • Unit 4: Antiviral Agents · 2 hours

      Identify the agents used in treating viral infections.. Learn about the antiretroviral agents used in treating HIV/AIDS.. Understand the importance of pharmacokinetics in the treatment of HIV-infected individuals.. Describe the mechanisms of action of various antiviral drugs..

13. Week 13Module 4: Chemotherapeutic Drugs

    • Unit 5: Antifungal Agents · 2 hours

      Understand the three categories of antifungal drugs.. Know the pharmacokinetics of antifungal agents.. Know the specific uses of antifungal agents.. Describe the mechanisms of action of amphotericin B, ketoconazole, nystatin, griseofulvin, and fluconazole..

    • Unit 5: Chemotherapy of Cancer · 2 hours

      Know the causes of cancer.. Understand the types of cancer.. Learn about the drugs used in cancer chemotherapy.. Describe the mechanisms of action of alkylating agents, nitrosoureas, antimetabolites, and plant alkaloids..