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BIO406

Parasitology and Immunology

  • Sciences
  • 400 level
  • 2 credit units
  • 83 pages
  • 5 units

This course on Parasitology and Immunology explores the body's defense mechanisms against infections. It covers different types of immunity, defense mechanisms, processes, functions, and the interaction of antibodies with antigens. The course delves into hypersensitivity, autoimmunity, and the immunology of tissue transplantation. Students will gain an understanding of infections, protection, and the roles of various cells and molecules in the immune response. The course aims to provide a comprehensive overview of parasitology and immunology.

About this course

Difficulty
Intermediate
Study hours
40 hours
Maths
None
Content
Theoretical
Practical work
No
How it is assessed
  • Assignments
  • Tutor marked assignments
  • Final examination

What you'll read

The real module and unit structure of BIO406, taken from the course material NOUN publishes.

One paragraph, so you can see how it reads

BIO406 · UNIT 2: INFECTION, IMMUNITY AND PROTECTION

Naturally acquired active immunity occurs when a person is exposed to a live pathogen, and develops a primary immune response, which leads to immunological memory. This type of immunity is “natural” because it is not induced by deliberate exposure. Many disorders of immune system function such as immunodeficiency and immuno-suppression can affect the formation of active immunity.

What you should be able to do

  1. Define and differentiate between various types of immunity.
  2. Explain the mechanisms of infection and the body's defense strategies.
  3. Describe the nature of antigens and their interaction with antibodies.
  4. Classify and explain the different types of hypersensitivity reactions.
  5. Discuss the causes and pathogenesis of autoimmunity.
  6. Explain the immunology of tissue transplantation and graft rejection.

What it prepares you for

Careers
  • Medical Laboratory Scientist
  • Immunologist
  • Research Scientist
  • Public Health Officer
  • Pharmaceutical Researcher
Where it is applied
  • Healthcare
  • Pharmaceuticals
  • Biotechnology
  • Research
  • Public Health

Where it gets hard

The units students slow down on, and what makes each one heavy.

  • Module 1: Immunity

    Unit 3: Antigen

    Understanding the complex interactions between antigens and antibodies requires a strong foundation in biochemistry and molecular biology.

  • Module 2: Hypersensitivity

    Unit 1: Hypersensitivity

    Differentiating between the various types of hypersensitivity reactions (I-IV) and their underlying mechanisms requires careful attention to detail.

A suggested way through it

Suggested

13 weeks, about 39 hours in total. Yours will differ.

  1. Week 1Module 1: Immunity
    • Unit 1: Immunity · 3 hours

      Define immunity and its historical context.. Describe the theories of immunity from ancient times to modern immunology.. Explain the different types of immunity: passive, active, innate, and acquired..

  2. Week 2Module 1: Immunity
    • Unit 2: Infection, Immunity and Protection · 3 hours

      Define infection and describe the chain of events for infections to occur.. Explain the differences between bacterial and viral infections.. Discuss prevention strategies, including hygiene, sanitation, and vaccination..

  3. Week 3Module 1: Immunity
    • Unit 3: Antigen · 3 hours

      Define antigen, immunogen, and epitope.. Explain the characteristics of antigens and their origin.. Describe the interaction of antibodies with antigens, including affinity and avidity..

  4. Week 4Module 2: Hypersensitivity
    • Unit 1: Hypersensitivity · 3 hours

      Describe hypersensitivity and its classification.. Explain the mechanisms of Type I hypersensitivity, including IgE-mediated reactions.. Discuss the role of mast cells, basophils, and other mediators in allergic reactions..

  5. Week 5Module 2: Hypersensitivity
    • Unit 1: Hypersensitivity · 3 hours

      Explain the mechanisms of Type II hypersensitivity, including antibody-mediated cytotoxicity.. Discuss the role of IgG and IgM antibodies and complement activation.. Provide examples of Type II hypersensitivity, such as drug-induced hemolytic anemia..

  6. Week 6Module 2: Hypersensitivity
    • Unit 1: Hypersensitivity · 3 hours

      Explain the mechanisms of Type III hypersensitivity, including immune complex formation.. Discuss the role of IgG and IgM antibodies and complement activation.. Provide examples of Type III hypersensitivity, such as serum sickness and lupus nephritis..

  7. Week 7Module 2: Hypersensitivity
    • Unit 1: Hypersensitivity · 3 hours

      Explain the mechanisms of Type IV hypersensitivity, including cell-mediated reactions.. Discuss the role of T lymphocytes and macrophages.. Provide examples of Type IV hypersensitivity, such as tuberculin reaction and contact dermatitis..

  8. Week 8Module 2: Hypersensitivity
    • Unit 2: Autoimmunity · 3 hours

      Describe autoimmunity and its causes.. Explain the role of sequestered auto-antigens and inappropriate MHC class II expression.. Discuss the defects in the generation of suppressor T cells..

  9. Week 9Module 2: Hypersensitivity
    • Unit 2: Autoimmunity · 3 hours

      Explain the concept of low-level autoimmunity and its potential benefits.. Discuss the role of autoimmunity in recognizing neoplastic cells and aiding rapid immune responses.. Describe the theories of immunological tolerance, including clonal deletion, anergy, and idiotype network..

  10. Week 10Module 2: Hypersensitivity
    • Unit 2: Autoimmunity · 3 hours

      Explain the genetic factors associated with autoimmunity, including genes related to immunoglobulins, T-cell receptors, and MHC.. Discuss the role of HLA DR2, DR3, and DR4 in autoimmune diseases.. Describe the environmental factors affecting autoimmunity, including infectious diseases and chemical agents..

  11. Week 11Module 2: Hypersensitivity
    • Unit 2: Autoimmunity · 3 hours

      Describe the pathogenesis of autoimmunity, including T-cell bypass, molecular mimicry, and cytokine dysregulation.. Explain the role of dendritic cell apoptosis and epitope spreading.. Discuss the mechanisms of autoimmune diseases..

  12. Week 12Module 2: Hypersensitivity
    • Unit 3: Immunology of Tissue Transplantation · 3 hours

      Identify the different types of transplants: autograft, allograft, and xenograft.. Describe the evidence that graft rejection is immunological, including first and second set reactions.. Explain the role of lymphocytes and antibodies in graft rejection..

  13. Week 13Module 2: Hypersensitivity
    • Unit 3: Immunology of Tissue Transplantation · 3 hours

      Describe the mechanism of graft rejection, including lymphocyte-mediated rejection and the role of antibodies.. Explain the prevention of graft rejection through tissue typing and the use of immunosuppressants.. Discuss the use of agents producing general immunosuppression and their side effects..

Preparing for the exam

What to do
  • Create detailed concept maps linking different types of immunity (innate, adaptive, passive, active) and their components.
  • Focus on understanding the mechanisms of each type of hypersensitivity reaction (Types I-IV) and their clinical manifestations.
  • Review the key differences between humoral and cell-mediated immunity, including the roles of B cells, T cells, and antibodies.
  • Practice identifying the key characteristics of different autoimmune diseases and their underlying genetic and environmental factors.
  • Study the mechanisms of graft rejection and the strategies used to prevent it, such as tissue typing and immunosuppression.
  • Use flashcards to memorize key terms and definitions related to parasitology and immunology.
  • Review all Tutor-Marked Assignments (TMAs) and self-assessment questions to identify areas of weakness and focus your study efforts.

Questions students ask about this course

What is BIO406 about?

This course on Parasitology and Immunology explores the body's defense mechanisms against infections. It covers different types of immunity, defense mechanisms, processes, functions, and the interaction of antibodies with antigens. The course delves into hypersensitivity, autoimmunity, and the immunology of tissue transplantation. Students will gain an understanding of infections, protection, and the roles of various cells and molecules in the immune response. The course aims to provide a comprehensive overview of parasitology and immunology.

How many units does BIO406 have?

BIO406, Parasitology and Immunology, has 5 units across 2 modules, over 83 pages of course material. You can read it one unit at a time.

How many credit units is BIO406?

BIO406 carries 2 credit units, at 400 level in Sciences.

Is BIO406 hard?

BIO406 is rated intermediate level, with no mathematical content. It is mostly theoretical work.

How long does BIO406 take to study?

About 40 hours of study, spread across its 5 units.

How is BIO406 assessed?

BIO406 is assessed by assignments, tutor marked assignments and final examination.

What can I do with BIO406?

Medical Laboratory Scientist, Immunologist, Research Scientist, Public Health Officer and Pharmaceutical Researcher.

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