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NSC224Health Sciences2 Unitsintermediate

MEDICAL BIOCHEMISTRY II

This course introduces students to intermediary metabolism and biological oxidation, essential for understanding allied and health sciences. It explores biochemical pathways that break down ingested molecules into functional materials and energy, covering both catabolic and anabolic reactions. Clinical conditions associated with metabolic pathway impairments are also discussed, providing a comprehensive overview of metabolic processes and their clinical relevance.

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45h
Study Time
13
Weeks
3h
Per Week
basic
Math Level
Course Keywords
MetabolismGlycolysisFatty Acid OxidationVitaminsAmino Acids

Course Overview

Everything you need to know about this course

Course Difficulty

Intermediate Level
Builds on foundational knowledge
65%
intermediate
➕
Math Level
Basic Math
🔬
Learning Type
Hands-on Practice

Course Topics

Key areas covered in this course

1

Glycolysis

2

Tricarboxylic Acid Cycle

3

Fatty Acid Oxidation

4

Vitamins

5

Trace Elements

6

Amino Acid Metabolism

7

Diabetes Mellitus

Total Topics7 topics

Requirements

Knowledge and skills recommended for success

NSC 223: Medical Biochemistry I

💡 Don't have all requirements? Don't worry! Many students successfully complete this course with basic preparation and dedication.

Assessment Methods

How your progress will be evaluated (7 methods)

Assignments

Comprehensive evaluation of course material understanding

Written Assessment

Tutor-Marked Assessments

Comprehensive evaluation of course material understanding

Written Assessment

Laboratory practical

Comprehensive evaluation of course material understanding

Written Assessment

Discussion Topic participation

Team-based learning and peer interaction

Group Work

Group assignment

Team-based learning and peer interaction

Group Work

Computer marked Assignment

Comprehensive evaluation of course material understanding

Written Assessment

Final Examination

Comprehensive evaluation of course material understanding

Computer Based Test

Career Opportunities

Explore the career paths this course opens up for you

Registered Nurse

Apply your skills in this growing field

Medical Laboratory Scientist

Apply your skills in this growing field

Nutritionist

Apply your skills in this growing field

Biomedical Researcher

Apply your skills in this growing field

Public Health Officer

Apply your skills in this growing field

Industry Applications

Real-world sectors where you can apply your knowledge

HealthcarePharmaceuticalsFood and NutritionResearch and Development

Study Schedule Beta

A structured 13-week journey through the course content

Week
1

Module 1: Carbohydrate Metabolism

3h

Unit 1: Glycolysis

3 study hours
  • •Understand the concept of digestion and absorption of carbohydrates.
  • •Explain the importance of the glycolytic pathway.
  • •Enumerate the different reactions which make up the pathway and the enzymes which catalyze these reactions.
Week
2

Module 1: Carbohydrate Metabolism

3h

Unit 2: Glycolysis II

3 study hours
  • •Give the gross and net ATP yield of glycolysis.
  • •List the glycolytic regulatory enzymes and their corresponding effectors.
  • •Explain the fates of Pyruvate.
Week
3

Module 1: Carbohydrate Metabolism

3h

Unit 3: Tricarboxylic Acid Cycle

3 study hours
  • •Describe TCA cycle in detail.
  • •Explain the Amphibolic nature of the TCA cycle.
  • •Explain the Anaplerotic nature of the TCA cycle.
Week
4

Module 2: Fatty Acid Metabolism

3h

Unit 1: Fatty Acid Oxidation

3 study hours
  • •Describe the activation of fatty acids and the transport of fatty acyl coAs into the mitochondria, and list the steps of β-oxidation.
  • •Outline the steps involved in β-oxidation.
  • •Calculate the net ATP yield from Palmitate oxidation.
Week
5

Module 2: Fatty Acid Metabolism

3h

Unit 2: Fatty Acid Oxidation 2

3 study hours
  • •Describe pathways for oxidation of unsaturated fatty acids and fatty acids with an odd number of carbon atoms.
  • •Describe α and ω oxidation of fatty acids.
  • •Outline the process by which fatty acid oxidation is regulated.
Week
6

Module 3: Vitamins and Trace Elements

3h

Unit 1: The Fat Soluble Vitamins

3 study hours
  • •Define fat soluble vitamins (FSV) and list all the FSV.
  • •Describe vitamin A.
  • •Describe vitamin D.
Week
7

Module 3: Vitamins and Trace Elements

3h

Unit 2: Water Soluble Vitamins

3 study hours
  • •List the biochemical functions, deficiency and natural sources of vitamin B1 (Thiamine).
  • •List the biochemical functions, deficiency and natural sources of vitamin B2
  • •Describe the biochemical functions, deficiency and natural sources of vitamin B3 (Niacin)
Week
8

Module 3: Vitamins and Trace Elements

3h

Unit 3: Trace Elements

3 study hours
  • •Distinguish between Macro and Microminerals.
  • •List important microminerals (Trace Elements) and enumerate the functions, food sources, required daily allowance, deficiency and toxicity symptoms of each trace mineral studied.
Week
9

Module 4: Amino Acid Metabolism

3h

Unit 1: Sources of Amino Acids

3 study hours
  • •Discuss the sources and Metabolism of Amino Acids.
  • •Describe the fate of free amino acids.
  • •Explain the digestion of dietary protein.
Week
10

Module 4: Amino Acid Metabolism

3h

Unit 2: Disorders of Amino Acid Metabolism

3 study hours
  • •Explain Phenylketonuria (PKU).
  • •Explain Albinism.
  • •Explain Alkaptonuria.
Week
11

Module 4: Amino Acid Metabolism

3h

Unit 3: Diabetes Mellitus

3 study hours
  • •Describe the metabolic changes that accompany Diabetes Mellitus.
  • •Explain the classification of Diabetes Mellitus and distinguish the different types of Diabetes in terms of metabolic features, symptoms and time of onset.
  • •Describe how Diabetes mellitus is diagnosed and the mode of action of medications used in treatment of Diabetes.
Week
12

Modules 1 & 2 Review

4h

Review of Modules 1 & 2

4 study hours
  • •Review key concepts from Modules 1 and 2.
  • •Practice problem-solving related to metabolic pathways.
  • •Complete assignments related to carbohydrate and fatty acid metabolism.
Week
13

Modules 3 & 4 Review

4h

Review of Modules 3 & 4

4 study hours
  • •Review key concepts from Modules 3 and 4.
  • •Practice problem-solving related to vitamins, trace elements, and amino acid metabolism.
  • •Complete assignments related to vitamins, trace elements, and amino acid metabolism.

This study schedule is in beta and may not be accurate. Please use it as a guide and consult the course outline for the most accurate information.

Course PDF Material

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Study Tips & Exam Preparation

Expert tips to help you succeed in this course

1

Create detailed flowcharts of each metabolic pathway (glycolysis, TCA cycle, fatty acid oxidation) to visualize the sequence of reactions.

2

Focus on understanding the regulatory enzymes in each pathway and how they are affected by different metabolites (ATP, AMP, citrate).

3

Practice drawing the structures of key molecules involved in metabolism (glucose, pyruvate, acetyl-CoA, fatty acids, amino acids).

4

Review the clinical conditions associated with metabolic disorders (diabetes, PKU, albinism) and their underlying biochemical causes.

5

Use flashcards to memorize the names and functions of the different vitamins and trace elements.

6

Work through practice problems involving calculations of ATP yield from different metabolic processes.

7

Pay close attention to the differences between Type 1 and Type 2 diabetes, including their causes, symptoms, and treatments.

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